The Basics of Cocaine

Of all the illegal drugs in our country, perhaps none is as well-known for its addiction and harmful effects on the user’s life as cocaine. According to a 2006 National Survey on Drug Use and Health, 35.3 million Americans aged 12 and older reported having used cocaine, and 8.5 million reported having used crack cocaine. There were an estimated 977,000 new users of cocaine in 2006—most were 18 or older when they first used cocaine. (1)

Cocaine addiction

Cocaine is a derivative of the leaves of the coca plant, which is either snorted, dissolved in water and injected, or smoked. While under the influence of cocaine, the user develops a “high”, which increases mental alertness and reduces fatigue. This high only lasts for a short time, and after as little as 5-15 minutes, the user may feel the need to administer the drug again in order to maintain the high feeling. In fact, this is one reason why cocaine is so addictive – the user is constantly trying to maintain that great feeling of euphoria.

Cocaine causes a high by increasing the level of dopamine in the brain, which in humans signals something pleasurable. In healthy people this signal is shut off after a short time, but in cocaine addicts, the dopamine is kept from being recycled and large amounts of it build up in the brain, causing the high. Tolerance to the high of dopamine is likely to occur, and more cocaine is needed to feel the good feeling. After a short time, the user is addicted and may need cocaine detox.

Cocaine’s Effects

Cocaine has many detrimental effects on the body, including headache, nausea, increased heart rate and blood pressure, decreased appetite, and problems with nosebleeds or with swallowing. Cocaine addicts are more likely to be irritable without their high, and suffer from anxiety, paranoia, and hallucinations. Other serious risks are heart attack, stroke, respiratory arrest, and seizure.

Predisposition to addiction

A study done by Hans Breiter and his colleagues from Massachusetts General Hospital (2) found that in cocaine addicts, the area of the brain that deals with decision making and preference is actually altered with cocaine use. The thinning that occurs in this region of the brain may explain why cocaine users become so addicted; their brain no longer cares about things other than the drug, and they aren’t able to make coherent decisions to stay away from the drug.

This study also found, however, that in drug abusers the overall thickness in the brain is more uniform than in non-drug users. Because this symmetry of thickness does not seem to be a result of drug use, researchers are beginning to think that some people have a predisposition to drug use.

Whatever the cause of addiction to cocaine, it is a disease. If you or someone you know is addicted to cocaine, it is important to get help right away. The risks of using cocaine make it a very unsafe drug, and many people have died suddenly from its effects. Find a drug treatment center to help deal with the addiction.

Sources
(1) Cocaine: Abuse With Alcohol Increases Deadliness 9/22/2008

(2) Thinner Cortex In Cocaine Addicts May Reflect Drug Use And A Pre-existing Disposition To Drug Abuse ScienceDaily Oct. 13, 2008

Cocaine and the Brain Ivanhoe Newswire Oct. 10, 2008